One way to find out how long a drug will last in your body is to measure its half-life. The half-life is the time it takes for half of the drug to be eliminated from the body. This is a lot of questions about time frames for how long can weed be detected in your system. And there is a lot of “pitfalls” with marijuana drug testing. Acetaminophen/Oxycodone - 1. how long does it stay in your system 2. how long show you wait before? Asked 16 May 2012 by taylorlin Updated 19 May 2012 To prevent an overdose of either medication it can be helpful to understand how long they stay in the body so that you don't risk overlapping a new dose of either ingredient with medication that's still circulating in your system. Wondering how long does cocaine stay in your system as in urine, blood and saliva. We have done an updated research in 2018 that cocaine can show up for up to 3 days in your body. Cocaine plasma and urine elimination take 1.5 hours and 19 hours respectively, but all that depend on many factors too. I know this is a long time since you posted so hope you managed to get off the horrible stuff! I've had to take 60mg of motphine for over 2 years for pain relief and due to being ill I didn't take it for few days now 4 days after taking the last tablet I still have the pain but the shivers etc have now gone thank god! How Long Does Tramadol Stay in your System. Generally tramadol will stay in your system for 1-2 days but this varies depending on your body and how it is tested. Percocet contains oxycodone and acetaminophen, both of which have risks for dangerous interactions and overdoses as long as they're in your system. You need to understand about the use, how oxycodone work, how long does oxycodone take to work, the side effect of oxycodone, etc. Before exploring how long kratom stays in the system of a user, it’s valuable to understand exactly how kratom works. Since it is such a new introduction in the U.S. market, a lot of people have misconceptions about kratom, or simply don’t know much about it.